Synthesis of Seven-membered Heterocyclic Compounds

Construction of Five-Membered Heterocyclic Compounds via Radical Cyclization

2-Phenoxyethanol derived diselenide and related compounds; synthesis of a seven-membered seleninate ester.

Syntheses of several diorganodiselenides and, in particular, a seven-membered cyclic seleninate ester derived from 2-phenoxyethanol are described. The seleninate ester was obtained from allyl (2-(2-hydroxyethoxy)phenyl) selenide through a series of oxidation and [2,3] sigmatropic rearrangement steps. The ester exhibits good GPx-like activity in the coupled reductase assay.

Synthesis of Some New Heterocyclic Compounds with Potential Biological Activity

A series of new 2-arylimino-3-aryl-5-[5?-(3,4-dichlorophenyl)-2?-furylidene]-4-thiazolidinones (3a-l) have been synthesised by the condensation of 5-(3,4-dichlorophenyl)-2-furaldehyde 1 with 2-arylimino-3-aryl-5H-4-thiazolidinones 2 in glacial acetic acid. The physical and spectral data of the synthesised compounds are determined. The synthesised compounds have been screened for their in vitro ...

Transition metals catalyzed synthesis novel heterocyclic compounds

Based on my research experience and academic career, my research plan is to develop new synthetic reactions to create heterocyclic molecules having useful properties as functional materials or biological activities. Reactions I am going to study on can be classified into the following two categories. Project 1: Transition metal-catalyzed cascade cyclization and oxidative cross couplings reactio...

comparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.

heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...